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Clearance decreased in patients with mild Clcr – mLminute to severe renal insufficiency endstage renal disease on hemodialysis and may result in increased adverse effects eg back pain No dosage adjustments are necessary in those with mild renal impairment Dosage adjustments based on degree of renal impairment See Renal Impairment under Dosage and Administration,  http://surveys.questionpro.com/a/TakeSurvey?id=2813230 cialis soft tablets,  hxbicr, 

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